PDRN, Exosomes & Regenerative Skincare: What Does the Science Actually Say?

Skincare has always borrowed terminology from medicine, but lately the vocabulary has become considerably more futuristic. Products and treatments promising “cellular regeneration,” “DNA repair,” exosomes, growth factors, and even “salmon DNA” are appearing everywhere from dermatology offices to social media feeds. Two ingredients getting particular attention are PDRN and exosomes. [...]

PDRN, Exosomes & Regenerative Skincare: What Does the Science Actually Say?2026-09-28T07:44:33-05:00

What Is “Microdosing” Accutane? Understanding Low-Dose Isotretinoin for Acne

Isotretinoin—often still referred to by its former brand name, Accutane—has been one of dermatology’s most effective treatments for severe and treatment-resistant acne for decades. But the traditional approach to isotretinoin treatment isn’t the only way dermatologists may use this medication. Increasingly, patients are hearing about “microdosing Accutane,” a popular term [...]

What Is “Microdosing” Accutane? Understanding Low-Dose Isotretinoin for Acne2026-09-29T08:47:19-05:00

Hyaluronic Acid Sheet Masks: The Hydration Step You May Be Using Wrong

Sometimes the simplest skincare products are the easiest to underestimate. Hyaluronic acid masks don't exfoliate, resurface, or dramatically accelerate cell turnover. Instead, they do something much more basic—and extremely important for healthy skin: they hydrate. We especially like biocellulose masks when skin feels dry, tight, stressed, or simply needs an [...]

Hyaluronic Acid Sheet Masks: The Hydration Step You May Be Using Wrong2026-09-17T10:48:14-05:00

Egg Masks Do Not Unplug Pores: What Dermatology Actually Shows

Have you heard about the kitchen-sink “pore-clearing” mask? Raw egg whites, sometimes mixed with lemon, honey, or baking soda is emerging as the latest pore cleansing craze. The promise is familiar: tighter skin, smaller pores, and blackheads that lift away as the mask peels. If you have tried this and [...]

Egg Masks Do Not Unplug Pores: What Dermatology Actually Shows2026-09-03T16:17:45-05:00

Tanning Beds and Melanoma: Why the Risk Is Real—and Safer Ways to Glow

We frequently see patients who used tanning beds in their teens or twenties and now face early skin cancers or significant photoaging. The desire for a quick, even tan is understandable—especially before events or during long Minnesota winters—but the science on indoor tanning is clear and concerning. Tanning beds and [...]

Tanning Beds and Melanoma: Why the Risk Is Real—and Safer Ways to Glow2026-08-21T08:51:26-05:00

Azelaic Acid and Tretinoin: Why They Should Not Be Used Together Without Careful Guidance

We regularly see patients who are excited about the complementary benefits of azelaic acid and tretinoin—clearer pores, faded dark spots, calmer redness—only to arrive frustrated by unexpected redness, flaking, or stinging after combining them. If you’ve read that these two ingredients “work well together” and layered them on the same [...]

Azelaic Acid and Tretinoin: Why They Should Not Be Used Together Without Careful Guidance2026-08-14T13:14:30-05:00

Zinc Oxide in Sunscreen vs. Diaper Rash Cream: Why One Belongs on Your Face (and the Other Doesn’t)

Have you heard about zinc oxide’s soothing, protective benefits and wondered whether the thick white cream from the baby aisle can double as a facial treatment? If you’ve scrolled past “face-basting” trends or considered swapping your sunscreen for a tube of diaper rash ointment, you’re far from alone. Zinc oxide [...]

Zinc Oxide in Sunscreen vs. Diaper Rash Cream: Why One Belongs on Your Face (and the Other Doesn’t)2026-08-06T09:18:30-05:00

What Is the Skin Barrier?

Often described as a “brick wall,” the skin barrier (stratum corneum) consists of skin cells (“bricks”) held together by lipids (“mortar”)—primarily ceramides, cholesterol, and fatty acids. It keeps moisture in, irritants and bacteria out, and supports overall skin health. When damaged, transepidermal water loss increases, leading to inflammation and sensitivity. [...]

What Is the Skin Barrier?2026-07-30T10:38:40-05:00

Retinoid 101: A Dermatologist’s Guide to Clearer Skin, Smoother Texture, and Youthful Results (Without the Frustration)

At Advanced Dermatology & Cosmetic Institute, we regularly see patients who are excited about the anti-aging and acne-fighting potential of retinoids but feel overwhelmed or discouraged by redness, flaking, or irritation. If you’ve tried a retinol serum only to experience dryness, sensitivity, or inconsistent results, you’re far from alone. Retinoids [...]

Retinoid 101: A Dermatologist’s Guide to Clearer Skin, Smoother Texture, and Youthful Results (Without the Frustration)2026-07-21T10:11:21-05:00

Perioral Dermatitis 101: Understanding the Rash Around Your Mouth, Common Triggers, and a Dermatologist’s Guide to Calming It

At Advanced Dermatology & Cosmetic Institute, we regularly see patients who are frustrated and self-conscious about a persistent red, bumpy rash around their mouth (and sometimes nose or eyes) that just won’t go away. If you’ve noticed clusters of small red bumps, pustules, or flaky patches circling your mouth—often while [...]

Perioral Dermatitis 101: Understanding the Rash Around Your Mouth, Common Triggers, and a Dermatologist’s Guide to Calming It2026-07-07T07:47:57-05:00