You’ve heard of sunburn, but what about margarita burn?

One day, you’re squeezing limes for a pitcher of margaritas by the pool. The next, you’ve got a strange, red streak down your wrist or a dark patch on your chest that looks nothing like a sunburn.

This reaction, often nicknamed margarita burn, is triggered when lime juice left on your skin is exposed to sunlight. The compounds in the juice interact with UV rays, causing cellular damage to the skin in a process known as phytophotodermatitis.

What Is Phytophotodermatitis?

Phytophotodermatitis sounds like a mouthful, but the concept is surprisingly simple.

Certain plants contain chemical compounds — most notably furocoumarins — that can make your skin hypersensitive to sunlight. When these compounds linger on your skin and are exposed to UV rays, they create a phototoxic reaction, meaning that the sunlight activates the chemical in a way that injures the skin.

This reaction is neither an allergic reaction nor a sunburn.

The skin damage comes from a chemical reaction between the compound and the light, and it can only happen when both “ingredients” are present. On its own, the plant doesn’t cause a rash, and the UV exposure, without the chemical, may not cause any unusual reaction. But together, they can produce blistering, inflammation, or a dark, bruise-like stain that appears seemingly out of nowhere.

What Does Phytophotodermatitis Look Like?

Phytophotodermatitis doesn’t look like a typical sunburn, and it doesn’t follow the same timeline either. That’s part of what makes it so easy to misread. The reaction can take a full day or sometimes longer to appear, and when it does, it rarely shows up in the usual places or patterns.

Unlike sunburn, which tends to affect areas of broad exposure, such as the shoulders, forehead, and chest, phytophotodermatitis often appears in irregular shapes. A splash of juice might leave a drip-like mark along your wrist. A brushed plant stem might create a vertical streak on your leg. You might even see fingerprints or handprints if the compound was transferred through touch. These patterns don’t match the broad, more evenly spread areas where you’d expect a sunburn.

Blistering is possible in both conditions, but it’s typically more localized to the area where your skin made contact with the chemical in phytophotodermatitis. This condition leaves behind a grayish or brown stain that can last for months, especially if you expose your skin to sunlight again before it fully heals.

Other Triggers That Sensitize Your Skin to Sun

Phytophotodermatitis isn’t limited to lime juice, several fruits, vegetable and plants contain compounds that can make your skin more reactive to sunlight.

Citrus Fruits

Lime is the classic culprit behind margarita burn, but it’s not the only fruit with this effect. Lemons, grapefruits, oranges, and other citrus fruits all contain furocoumarins. Even if you’re not planning on drinking that day, the risk isn’t limited to beachside cocktails. It can happen while slicing lemons for iced tea, zesting citrus for a marinade, or squeezing lemon over your grilled salmon. If the juice or oils from the zest aren’t washed off promptly, even a small amount can trigger a reaction once UV light is added to the mix.

Fragrances and Essential Oils

Thought you were safe once you stepped out of the kitchen? Not quite. Citrus oils in your favorite summer fragrances can also introduce furocoumarins to your skin. Bergamot, lemon, grapefruit, and other essential oils are commonly found in perfumes and body sprays, particularly those with light, summery scents. If you head into the sun without protection after spritzing your neck, shoulders, décolletage, or wrists, it can leave behind streaks of pigmentation that take weeks to fade.

Wild Plants and Garden Greens

Celery, parsnip, and dill are known offenders, and so are fig trees, which produce a latex-like sap that can irritate the skin when activated by UV light.

However, the most dangerous example of a phytophotodermatitis-causing plant is giant hogweed, an invasive plant found in parts of the U.S. Its sap contains exceptionally high levels of furocoumarins, so just brushing against its stalks can cause severe blistering and deep, persistent pigmentation. Even cow parsnip, a smaller relative, can trigger similar damage in more mild climates.

How to Prevent Phytophotodermatitis

The best way to avoid phytophotodermatitis is to wash your skin thoroughly after handling citrus, fresh herbs, or wild plants, especially if you plan to spend time outside. You should also double-check the ingredients in your fragrances before going out for the day. Most importantly, always wear broad-spectrum sunscreen. Look for mineral-based sunscreens with ingredients like zinc oxide or titanium dioxide, which are less likely to irritate sensitive or reactive skin.

How to Treat Phytophotodermatitis

There’s no quick fix for phytophotodermatitis, but most cases resolve on their own with time and proper care.

If you notice redness or swelling within the first day or two, apply a cool compress to calm the skin. You can also use an over-the-counter hydrocortisone cream to reduce inflammation and itching.

Once the initial inflammation calms, you may be left with patches of grayish or brown pigmentation. These hyperpigmented areas aren’t permanent, but you’ll need to be very diligent about sun protection to speed up the healing process. Allowing the area to soak in even more UV light can cause it to darken or prolong discoloration.

When to Check In With Your Dermatologist

Phytophotodermatitis often gets mistaken for a sunburn or an allergic reaction, so getting a clear diagnosis can save you a lot of guesswork. Dr. Elizabeth Briden of Advanced Dermatology & Cosmetic Institute can help you figure out what’s going on and what to do next, especially if the pigment isn’t fading as it should.

You can also browse our selection of medical-grade sun protection from dermatologist-trusted, clinically-tested brands, including sunscreen, Colorescience, Revision Skincare, and more.